{"id":35893,"date":"2024-09-27T11:23:26","date_gmt":"2024-09-27T09:23:26","guid":{"rendered":"https:\/\/yuboost.com\/?p=35893"},"modified":"2026-03-10T14:26:16","modified_gmt":"2026-03-10T13:26:16","slug":"what-is-nad","status":"publish","type":"post","link":"https:\/\/yuboost.com\/en\/vitamins\/what-is-nad\/","title":{"rendered":"Nad+"},"content":{"rendered":"<div>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/07\/NAD.png\" alt=\"nad+\"><\/p>\n<\/div>\n<h1>NAD+: definition, role, benefits, and link to longevity<\/h1>\n<div>\n<p><strong>NAD+<\/strong> is a <strong>vital<\/strong> coenzyme found in all our cells. It supports <strong>energy production<\/strong>, <strong>DNA repair<\/strong>, <strong>mitochondrial function<\/strong>, and contributes to <strong>healthy aging<\/strong>.<\/p>\n<p>As we age, its levels decline, which can result in fatigue, cognitive decline, and increased vulnerability to chronic diseases.<\/p>\n<p>Discover our page on <a href=\"https:\/\/yuboost.com\/en\/iv-therapy\/nad\/\">NAD+ therapies (IV Therapy)<\/a>, available at home in Switzerland.<\/p>\n<\/div>\n<div>\n<h2 class=\"uk-h5\">Table of Contents<\/h2>\n<ul class=\"uk-list uk-list-decimal uk-margin-remove\">\n<li><a href=\"#definition\">What is NAD+?<\/a><\/li>\n<li><a href=\"#roles\">The physiological roles of NAD+<\/a><\/li>\n<li><a href=\"#bienfaits\">The benefits of NAD+ in humans<\/a><\/li>\n<li><a href=\"#declins\">NAD+ decline with age<\/a><\/li>\n<li><a href=\"#longevite\">NAD+ and longevity: what science says<\/a><\/li>\n<li><a href=\"#solutions\">Our Yuboost solutions<\/a><\/li>\n<li><a href=\"#faq\">FAQ \u2013 NAD+<\/a><\/li>\n<\/ul>\n<\/div>\n<h2>What is NAD+ ?<\/h2>\n<div>\n<p style=\"text-align: left;\">NAD+ (<em>nicotinamide adenine dinucleotide<\/em>) is a universal coenzyme involved in hundreds of metabolic reactions. Without NAD+, <strong>ATP<\/strong> production and cellular homeostasis cannot be maintained.<\/p>\n<p style=\"text-align: left;\"><strong>Key mechanisms<\/strong>:<\/p>\n<ul style=\"text-align: left;\">\n<li style=\"text-align: left;\"><strong>Electron transport<\/strong> in cellular respiration (NAD+ \u2192 NADH), essential for oxidative phosphorylation and ATP synthesis.<\/li>\n<li style=\"text-align: left;\"><strong>Longevity regulation<\/strong>: substrate for <strong>sirtuins<\/strong> (gene expression, cellular stress response) and <strong>PARP<\/strong> (DNA repair).<\/li>\n<li style=\"text-align: left;\"><strong>Immune signaling<\/strong> via <strong>CD38<\/strong> and maintenance of mitochondrial redox balance.<\/li>\n<\/ul>\n<p style=\"text-align: left;\">In practice, NAD+ directly connects energy metabolism, cellular repair, and resistance to aging.<\/p>\n<\/div>\n<h2>The physiological roles of NAD+<\/h2>\n<div>\n<p>Beyond its definition, NAD+ is involved in essential cellular mechanisms that determine our health and longevity.<\/p>\n<p>A sustained imbalance in NAD+ metabolism can disrupt physiological functions and lead to diseases such as metabolic disorders, cancer, premature aging, and neurodegenerative conditions.<\/p>\n<p>Here are the main areas where its action is critical:<\/p>\n<\/div>\n<ul>\n<li>\n<h3>\n<h3>Cellular energy production (ATP)<\/h3>\n<\/h3>\n<div>\n<p>\n    NAD+ acts as a cellular &#8220;battery.&#8221; It captures and transports electrons during metabolic reactions,<br \/>\n    enabling the production of <strong>ATP<\/strong>, the body&#8217;s primary energy source.\n<\/p>\n<p>\n    During glycolysis and the Krebs cycle, NAD+ is reduced to NADH, which then feeds the mitochondrial<br \/>\n    respiratory chain and oxidative phosphorylation. This process results in the synthesis of large amounts of ATP.\n<\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>DNA repair and protection<\/h3>\n<\/h3>\n<div>\n<p>\n    NAD+ is essential for <strong>DNA repair<\/strong>. It serves as a substrate for PARP, an enzyme<br \/>\n    activated during DNA breaks. At the same time, it activates <strong>sirtuins<\/strong>, which regulate<br \/>\n    gene expression and contribute to longevity mechanisms.\n<\/p>\n<p>\n    Low levels of NAD+ lead to an accumulation of genetic damage, promoting premature aging, cancer,<br \/>\n    and degenerative diseases.\n<\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>Mitochondrial function and oxidative stress<\/h3>\n<\/h3>\n<div>\n<p>\n    The <strong>mitochondria<\/strong> are the &#8220;powerhouses&#8221; of our cells. NAD+ acts directly by supporting<br \/>\n    cellular respiration and regulating oxidative stress.\n<\/p>\n<p>\n    Studies show that increasing NAD+ stimulates <strong>mitochondrial biogenesis<\/strong> and activates<br \/>\n    protective pathways such as <strong>PGC1\u03b1<\/strong> and sirtuins.\n<\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>Immune function and neuroprotection<\/h3>\n<\/h3>\n<div>\n<p>\n    NAD+ also plays a role in <strong>immune signaling<\/strong> and the proper functioning of the nervous system.<br \/>\n    It influences neurotransmitter release and helps protect neurons against oxidative stress.\n<\/p>\n<\/div>\n<\/li>\n<\/ul>\n<p><img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/09\/NAD_phys.svg\" alt=\"nad+\"><\/p>\n<h2>The benefits of NAD+ in humans<\/h2>\n<ul>\n<li>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/04\/cerveau.png\" alt=\"connexion neuronales\"><\/p>\n<h3>Improves memory, concentration and mental clarity<\/h3>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/03\/cellulaire.png\" alt=\"connexion neuronales\"><\/p>\n<h3>Contributes to slowing down cellular aging<\/h3>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/12\/8.png\" alt=\"anti depresseur\"><\/p>\n<h3>Promotes physical recovery after sports, stress or burnout<\/h3>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/04\/perfomance-athletique.png\" alt=\"perfomance athletique\"><\/p>\n<h3>Increases endurance<\/h3>\n<\/li>\n<\/ul>\n<h2>Decline in NAD+ with age<\/h2>\n<div>\n<p>NAD+ is constantly consumed by all physical and mental functions, and unfortunately, our physiological system uses up NAD+ faster than it can be replenished once we reach our thirties.<\/p>\n<p>The aging process increases the risk of DNA damage, inflammation, and reduced mitochondrial function, which in turn negatively affects the body&#8217;s ability to produce NAD+.<\/p>\n<p>On average, <strong>NAD+ levels drop by 50% between ages 40 and 60,<\/strong> representing the scientific trigger for the decline of many basic physiological and physical functions.<\/p>\n<\/div>\n<p><img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/09\/Capture-decran-2024-09-20-a-09.42.25.png\" alt=\"\"><\/p>\n<h3>What is causing the decline of NAD?<\/h3>\n<ul>\n<li>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/09\/1.png\" alt=\"\"><\/p>\n<h3>Lifestyle choices<\/h3>\n<div>\n<p>Various lifestyle choices can negatively impact our NAD+ levels, such as stress, poor nutrition, an imbalanced work-life schedule, and reduced or poor-quality sleep.<\/p>\n<\/div>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/09\/2.png\" alt=\"\"><\/p>\n<h3>Substance abus<\/h3>\n<div>\n<p>Excessive alcohol, nicotine, recreational drugs, prescription medications, or other substances reduce NAD+ levels.<\/p>\n<\/div>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/09\/3.png\" alt=\"ageing\"><\/p>\n<h3>Aging<\/h3>\n<div>\n<p>Aging is most often associated with a decrease in NAD+ levels. Levels drop by half by middle age, which impacts the body\u2019s ability to combat age-related conditions and diseases.<\/p>\n<\/div>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/09\/4-1.png\" alt=\"chronic diseases\"><\/p>\n<h3>Chronic diseases<\/h3>\n<div>\n<p>Chronic diseases are generally the result of mitochondrial dysfunction, which can be triggered by a decrease in NAD+ levels.<\/p>\n<\/div>\n<\/li>\n<\/ul>\n<h3>How to increase your NAD+ levels?<\/h3>\n<ul>\n<li>\n<h3><img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/04\/65.png\" alt=\"icon\" width=\"50\" style=\"margin-right:6px; vertical-align:middle;\"> Natural solutions<\/h3>\n<div>\n<ul>\n<li>Diet rich in vitamin B3 (niacin, tryptophan).<\/li>\n<li>Regular physical activity.<\/li>\n<li>Restorative sleep.<\/li>\n<li>Stress management and a balanced lifestyle.<\/li>\n<\/ul>\n<\/div>\n<\/li>\n<li>\n<h3><img decoding=\"async\" src=\"https:\/\/yuboost.com\/wp-content\/uploads\/2025\/04\/vitamines-a-domicile.png\" alt=\"icon\" width=\"50\" style=\"margin-right:6px; vertical-align:middle;\"> Supplements and research<\/h3>\n<div>\n<p>\n  NAD+ precursors such as <strong>nicotinamide riboside (NR)<\/strong> and<br \/>\n  <strong>nicotinamide mononucleotide (NMN)<\/strong> are the subject of numerous studies.<br \/>\n  They appear promising for supporting NAD+ levels, but research is still ongoing.\n<\/p>\n<\/div>\n<\/li>\n<li>\n<h3><img decoding=\"async\" src=\"https:\/\/yuboost.com\/wp-content\/uploads\/2025\/09\/ICONE-YUBOOST.png\" alt=\"icon\" width=\"50\" style=\"margin-right:6px; vertical-align:middle;\"> NAD+ infusion<\/h3>\n<div>\n<p>\n  <strong>NAD+ therapy<\/strong> via intravenous infusion is the most effective way to quickly boost NAD+ levels.<br \/>\n  It delivers NAD+ directly into the bloodstream, providing significant benefits for brain function, energy levels, and overall performance.<br \/>\n  <a href=\"https:\/\/yuboost.com\/en\/iv-therapy\/nad\/\">NAD+ IV Therapy<\/a>.\n<\/p>\n<\/div>\n<\/li>\n<\/ul>\n<h2>NAD+ and longevity: what science says<\/h2>\n<div>\n<p>NAD+ is directly linked to aging mechanisms.<\/p>\n<p>Its gradual decline leads to impaired mitochondrial function, reduced DNA repair, and dysregulation of gene expression\u2014all factors that accelerate cellular decline.<\/p>\n<p>Numerous studies confirm its central role in longevity.<\/p>\n<\/div>\n<ul>\n<li>\n<h3>NAD+ and sirtuins in aging and disease<\/h3>\n<div>\n<p>\u279d Shows the role of NAD+ in activating sirtuins, proteins involved in longevity and aging regulation.<\/p>\n<p><strong>Associated study:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23454760\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a><\/p>\n<\/div>\n<\/li>\n<li>\n<h3>Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging<\/h3>\n<div>\n<p>\u279d Describes how the decline of NAD+ with age disrupts communication between the nucleus and mitochondria, accelerating aging.<\/p>\n<p><strong>Associated study:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24360282\/\" target=\"_blank\" rel=\"noopener\">PubMed \u2013 24360282<\/a><\/p>\n<\/div>\n<\/li>\n<li>\n<h3>NAD+ and redox metabolism in aging and disease<\/h3>\n<div>\n<p>\u279d Comprehensive review of the link between NAD+, aging, and age-related diseases (neurodegenerative, metabolic, cardiovascular).<\/p>\n<p><strong>Associated study:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29779976\/\" target=\"_blank\" rel=\"noopener\">PubMed \u2013 29779976<\/a><\/p>\n<\/div>\n<\/li>\n<li>\n<h3>NAD+ in aging, metabolism, and neurodegeneration<\/h3>\n<div>\n<p>\u279d Highlights the importance of NAD+ in protecting against age-related neurodegenerative diseases.<\/p>\n<p><strong>Associated study:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30586782\/\" target=\"_blank\" rel=\"noopener\">PubMed \u2013 30586782<\/a><\/p>\n<\/div>\n<\/li>\n<\/ul>\n<h2>The scientific mechanisms of NAD+<\/h2>\n<ul>\n<li>\n<h3>\n<h3>NAD+ and glycolysis<\/h3>\n<\/h3>\n<div>\n<p>Glycolysis is the first step in cellular energy production.<br \/>NAD+ acts as an electron acceptor during the breakdown of glucose into pyruvate, producing NADH that will then feed mitochondrial respiration.<\/p>\n<p>\ud83d\udd2c <strong>Associated study:<\/strong> <a>The NAD+\/NADH ratio: linking glycolytic metabolism to transcriptional regulation<\/a><\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>NAD+ and the Krebs cycle (linking reaction)<\/h3>\n<\/h3>\n<div>\n<p>In the mitochondria, NAD+ captures electrons from nutrient oxidation and transfers them to the respiratory chain, thereby supporting ATP production and energy metabolism.<\/p>\n<p><strong>Associated study:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24125851\/\" target=\"_blank\" rel=\"noopener\">NAD+ metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus<\/a><\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>Electron transport chain and oxidative phosphorylation<\/h3>\n<\/h3>\n<div>\n<p>The NADH produced in glycolysis and the Krebs cycle donates its electrons to the electron transport chain, located in the mitochondrial membrane.<br \/>These electrons drive ATP synthase, which produces the majority of ATP required for cellular function.<\/p>\n<p><strong>Associated study:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29916692\/\" target=\"_blank\" rel=\"noopener\">Mitochondrial electron transport chain, NAD+ metabolism, and oxidative stress<\/a><\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>The redox reaction of NAD+<\/h3>\n<\/h3>\n<div>\n<p>\nThe NAD+\/NADH pair plays a fundamental role in redox reactions. NAD+ is the oxidized form, and NADH is the reduced form.<br \/>\nThese electron exchanges are at the heart of cellular respiration, DNA repair, and the maintenance of redox balance.\n<\/p>\n<p><strong>Associated study:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29779976\/\" target=\"_blank\" rel=\"noopener\"><br \/>\nNAD+ and redox metabolism in aging and disease<\/a><\/p>\n<\/div>\n<\/li>\n<\/ul>\n<h2>Our NAD+ solutions<\/h2>\n<div>\n<p>At Yuboost, we go beyond the scientific findings by offering two complementary solutions: <strong>a micronutrient assessment<\/strong> to measure your levels and create a personalized profile, and <strong>intravenous NAD+ infusions<\/strong> to restore your reserves and optimize your performance. By combining analysis with targeted intervention, we help you turn knowledge about NAD+ into real benefits for your health and longevity.<\/p>\n<\/div>\n<ul>\n<li>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/09\/4-1.png\" alt=\"bilan nad+\"><\/p>\n<h3>NAD+ Assessment (At-Home Kit)<\/h3>\n<div>\n<p>Accurately measure your NAD+ levels and their cofactors with a quick analysis, then receive a detailed medical interpretation and personalized recommendations to optimize your performance, strengthen your defenses, and preserve cellular longevity.<\/p>\n<\/div>\n<p><a href=\"https:\/\/yuboost.com\/en\/check-up\/nad\/\">Learn more<\/a><\/p>\n<\/li>\n<li>\n<p>        <img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/09\/3-1.png\" alt=\"perfusion nad\"><\/p>\n<h3>Intravenous NAD+ Infusion (Intervention)<\/h3>\n<div>\n<p>Effectively restore your NAD+ levels by improving mitochondrial health and enhancing cellular repair mechanisms to boost energy production, support mental clarity, and slow the effects of aging.<\/p>\n<\/div>\n<p><a href=\"https:\/\/yuboost.com\/en\/iv-therapy\/nad\/\">Discover the NAD+ infusion<\/a><\/p>\n<\/li>\n<\/ul>\n<h2>All about NAD+<\/h2>\n<ul>\n<li>\n<h3>\n<h3>What is NAD+ in simple terms?<\/h3>\n<\/h3>\n<div>\n<p>It is a coenzyme present in all our cells, essential for energy production and DNA repair.<\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>What are the benefits of NAD+?<\/h3>\n<\/h3>\n<div>\n<p>Increased energy, cognitive support, anti-aging effects, physical recovery, and immune protection.<\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>What is the difference between NAD, NADH, and NADPH?<\/h3>\n<\/h3>\n<div>\n<p>NAD+ is the oxidized form, NADH is the reduced form, and NADPH is involved in anabolic reactions (synthesis and protection against oxidative stress).<\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>Why do NAD+ levels decrease with age?<\/h3>\n<\/h3>\n<div>\n<p>Natural aging, oxidative stress, DNA damage, chronic inflammation, and an unbalanced lifestyle.<\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>Can NAD+ levels be restored?<\/h3>\n<\/h3>\n<div>\n<p>Low NAD+ levels can be caused by deficiencies in the synthesis\/salvage pathways, excessive DNA damage from free radicals or ultraviolet light, or chronic immune activation.<\/p>\n<p>Activation of PARPs in the presence of excessive or accelerated DNA lesions leads to NAD+ depletion. When NAD+ levels become extremely low, adenosine triphosphate (ATP) production decreases, ATP reserves are consumed, and ultimately, cell death occurs. Increased activity of CD38 and other NAD-consuming ectoenzymes during chronic immune activation also depletes NAD+.<\/p>\n<p>Declining NAD+ levels may be a major factor in aging and age-related degenerative diseases affecting the heart, brain, liver, kidneys, and skin.<\/p>\n<\/div>\n<\/li>\n<li>\n<h3>\n<h3>How to restore NAD+ levels?<\/h3>\n<\/h3>\n<div>\n<p>Healthy lifestyle (sleep, nutrition, exercise), supplements (NR, NMN), and especially NAD+ IV infusions.<\/p>\n<\/div>\n<\/li>\n<\/ul>\n<div>\n<p>For more information, contact us at <a href=\"mailto:info@yuboost.com\">info@yuboost.com<\/a><\/p>\n<\/div>\n<p><p>\n        <a href=\"https:\/\/yuboost.com\/en\/booking\/\">Book an appointment<\/a>\n    <\/p>\n<\/p>\n<h2>Discover all our vitamins<\/h2>\n<div>\n<\/div>\n<p><!--more--><br \/>\n<!-- {\"type\":\"layout\",\"children\":[{\"type\":\"section\",\"props\":{\"image_loading\":true,\"image_position\":\"top-center\",\"image_size\":\"contain\",\"media_visibility\":\"m\",\"padding_bottom\":\"small\",\"padding_top\":\"small\",\"status\":\"disabled\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"props\":{\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"width\":\"default\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"image\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/09\/Injection-Selenium-1-1.png\",\"image_alt\":\"Injection NAD+\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}},{\"type\":\"breadcrumbs\",\"props\":{\"show_current\":true,\"show_home\":true}}]}]}],\"name\":\"Post\"},{\"type\":\"section\",\"props\":{\"animation\":\"fade\",\"animation_delay\":\"200\",\"image_position\":\"center-center\",\"padding_bottom\":\"xsmall\",\"padding_top\":\"xsmall\",\"status\":\"disabled\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"block_align\":\"center\",\"content\":\"What is NAD+ ?\",\"id\":\"definition\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"text_align\":\"center\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"center\",\"title_color\":\"primary\",\"title_element\":\"h1\",\"title_style\":\"h1\"}},{\"type\":\"text\",\"props\":{\"block_align\":\"center\",\"column_breakpoint\":\"m\",\"content\":\"NAD+ IV Therapy is at the forefront of the exponential growth in preventative health innovation, human performance and the elongating\\nlife-span space.\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"maxwidth\":\"xlarge\",\"text_align\":\"center\"}}]}]},{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"image\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/09\/IS-INVOLVED-IN-ALL-BODY-FUNCTIONS-NAD-is-involved-in-hundreds-of-metabolic-functions-ranging-from-energy-creation-to-maintaining-healthy-DNA.png\",\"image_alt\":\"NAD+\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"image_width\":600,\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"text_align\":\"center\"}}]}]}]},{\"type\":\"section\",\"props\":{\"animation\":\"fade\",\"animation_delay\":\"200\",\"image_position\":\"center-center\",\"status\":\"disabled\",\"style\":\"muted\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"props\":{\"layout\":\"2-3,1-3\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"2-3\",\"width_small\":\"2-3\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"The critical role of NAD+\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"title_color\":\"primary\",\"title_element\":\"h2\",\"title_style\":\"h2\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>NAD+ is an essential housekeeping molecule found in every cell of the body, participating in numerous metabolic pathways. It serves as a vital cofactor and driving force for various critical cellular processes, such as energy metabolism, mitochondrial function, biosynthesis, gene expression, DNA repair, immune function, and ageing.<\/p>\n\n\\n\n\n<p>As a coenzyme, NAD+ performs two crucial functions: it acts as an electron transporter in cellular respiration and adenosine triphosphate (ATP) production, and it also serves as a substrate for poly (ADP-ribose) polymerase (PARP) and sirtuin (SIRT) enzymes, which are involved in DNA repair, gene regulation, and cell signalling - as well as being a substrate for CD38 ectoenzymes.<\/p>\n\n\\n\n\n<p>A sustained imbalance in NAD+ metabolism can disrupt physiological functions, potentially leading to diseases such as metabolic disorders, cancer, premature ageing, and neurodegenerative conditions. The impact of NAD+ deficiency on various diseases through the manipulation of cellular communication networks can be mitigated by NAD+ therapeutic intervention.<\/p>\n\n\\n\n\n<p>In essence, without NAD+, we would die. NAD+ is as vital to our bodies as oxygen. By enhancing and optimising NAD+ levels through therapeutic intervention, we can improve both mental and physical human performance and extend our lifespan.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}},{\"type\":\"headline\",\"props\":{\"content\":\"WHAT IS NAD+ USED FOR PHYSIOLOGICALLY?\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"title_color\":\"primary\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"s\",\"content\":\"\n\n<ul>\\n\n\n<li>Energy Production (ATP)<\/li>\n\n\\n\n\n<li>Chromosome Stability<\/li>\n\n\\n\n\n<li>DNA Repair (PARP 1)<\/li>\n\n\\n\n\n<li>Immune Cell Signalling<\/li>\n\n\\n\n\n<li>Telomere Elongating<\/li>\n\n\\n\n\n<li>Neurotransmitter (Brain Health)<\/li>\n\n\\n\n\n<li>Longevity Mechanisms<\/li>\n\n\\n<\/ul>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"style\":\"card-secondary\",\"vertical_align\":\"middle\",\"width_medium\":\"1-3\",\"width_small\":\"1-3\"},\"children\":[{\"type\":\"image\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/09\/2-1.png\",\"image_alt\":\"Nad+\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"image_width\":2000,\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"text_align\":\"center\"}}]}]}]},{\"type\":\"section\",\"props\":{\"animation\":\"fade\",\"animation_delay\":\"250\",\"image_position\":\"center-center\",\"status\":\"disabled\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"small\"},\"children\":[{\"type\":\"row\",\"props\":{\"layout\":\"3-5,2-5\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"3-5\",\"width_small\":\"3-5\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"NAD+ &amp; GLYCOLYSIS\",\"id\":\"bienfaits\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"maxwidth\":\"large\",\"text_align\":\"left\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"center\",\"title_color\":\"primary\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>Figure a. shows the series of steps that make up glycolysis. These steps all happen in the cytoplasm of a cell.<\/p>\n\n\\n\n\n<ul>\\n\n\n<li>Glycolysis is the splitting, or lysis, of glucose. It takes place in the cytoplasm of a cell. \u2022 Glycolysis is a series of reactions (steps) in which a glucose molecule is eventually split into pyruvate (links Glycolysis to Krebs cycle).<\/li>\n\n\\n\n\n<li>Hydrogen is transferred to the carrier molecule NAD (nicotinamide adenine dinucleotide). The NAD is now reduced NAD. Two molecules of reduced NAD are produced for each molecule of glucose entering Glycolysis. The hydrogens carried by reduced NAD can easily be transferred to other molecules.<\/li>\n\n\\n<\/ul>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"2-5\",\"width_small\":\"2-5\"},\"children\":[{\"type\":\"image\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/09\/IS-INVOLVED-IN-ALL-BODY-FUNCTIONS-NAD-is-involved-in-hundreds-of-metabolic-functions-ranging-from-energy-creation-to-maintaining-healthy-DNA.-1-1.png\",\"image_alt\":\"nad\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]}]},{\"type\":\"row\",\"props\":{\"layout\":\"1-3,2-3\",\"margin_bottom\":\"xlarge\",\"margin_top\":\"xlarge\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"1-3\",\"width_small\":\"1-3\"},\"children\":[{\"type\":\"image\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/09\/Capture-decran-2024-09-19-a-20.45.18.png\",\"image_alt\":\"nad+\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"2-3\",\"width_small\":\"2-3\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"THE LINK REACTION &amp; KREBS CYCLE\",\"id\":\"bienfaits\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"maxwidth\":\"large\",\"text_align\":\"left\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"center\",\"title_color\":\"primary\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>NAD+ participates in energy creation by acting as a delivery mechanism. This molecule donates and accepts electrons to and from enzymes in the mitochondrial membrane.<\/p>\n\n\\n\n\n<p>It is these electrons that fuel chemical reactions in the mitochondria. Without a sufficient supply of NAD+, the mitochondria can\u2019t adequately convert the nutrients from the foods we eat into usable energy.<\/p>\n\n\\n\n\n<p>The crucial role of NAD+ in different biological functions such as ageing, metabolism, mitochondrial function, immunological pathways, oxidative stress, gene expression, and apoptosis has been extensively investigated. Many studies have found that altered and reduced NAD+ levels play an important role in stimulating metabolic disorders, neurodegenerative disorders and tumorigenesis.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]}]},{\"type\":\"row\",\"props\":{\"layout\":\"3-5,2-5\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"3-5\",\"width_small\":\"3-5\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"ELECTRON TRANSPORT CHAIN &amp; OXIDATIVE PHOSPHORYLATION\",\"id\":\"bienfaits\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"maxwidth\":\"large\",\"text_align\":\"left\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"center\",\"title_color\":\"primary\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"Reduced NAD is produced in Glycolysis and in the Krebs cycle. The reduced NAD from Glycolysis\\nwas formed in the cytoplasm, but it can pass through the mitochondrial envelope and enter the\\nmatrix. These reduced NAD molecules move from the mitochondrial matrix to the inner\\nmembrane. Here, the hydrogens that they are carrying are removed. These hydrogens are later\\nused to produce large amounts of ATP-by-ATP synthase.\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"2-5\",\"width_small\":\"2-5\"},\"children\":[{\"type\":\"image\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/09\/Capture-decran-2024-09-19-a-20.53.49.png\",\"image_alt\":\"nad\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]}]}]},{\"type\":\"section\",\"props\":{\"animation\":\"fade\",\"animation_delay\":\"200\",\"image_position\":\"center-center\",\"status\":\"disabled\",\"style\":\"muted\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"THE REDOX REACTION OF NAD\",\"id\":\"bienfaits\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"maxwidth\":\"large\",\"text_align\":\"left\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"center\",\"title_color\":\"primary\",\"title_element\":\"h3\",\"title_style\":\"h3\"}}]}]},{\"type\":\"row\",\"props\":{\"layout\":\"1-3,2-3\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"1-3\",\"width_small\":\"1-3\"},\"children\":[{\"type\":\"image\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/09\/IS-INVOLVED-IN-ALL-BODY-FUNCTIONS-NAD-is-involved-in-hundreds-of-metabolic-functions-ranging-from-energy-creation-to-maintaining-healthy-DNA.-2.png\",\"image_alt\":\"THE REDOX REACTION OF NAD\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"2-3\",\"width_small\":\"2-3\"},\"children\":[{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>Cells obtain energy during cellular respiration by oxidising food molecules such as glucose. The energy derived from these actions is used to form ATP. The two forms of NAD constitute a redox couple. This term is used to describe reduced and oxidised forms of the same molecule. The NAD+ is the oxidised form, that is, a state in which it loses an electron. NADH is a reduced form of the molecule, which means that it gains the electron lost by NAD+. The redox reaction described in Figure 1 involves electron transfers which play a central role in energy creation. NAD+ is the main carrier of electrons in the energy-producing processes that take place in a cell\u2019s mitochondria. Mitochondria are known as the \u201cpowerhouses of the cell. \u201d These membrane-bound organelles are found in almost every living cell in the body, including the heart, brain, muscles, and lungs. They generate most of the energy needed to power the cell's biochemical reactions. The energy produced by the mitochondria is stored in the adenosine triphosphate molecule (ATP).<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]}]},{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"style\":\"card-primary\"},\"children\":[{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>In preclinical, proof-of-principle studies, increased NAD+ levels have been shown to induce mitochondrial biogenesis and enhanced natural pathways that are key to improving mitochondrial health, such as sirtuins and PGC1alpha.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]}]},{\"type\":\"row\",\"props\":{\"layout\":\"2-3,1-3\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"2-3\",\"width_small\":\"2-3\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"NAD+ THERAPY TARGETS ALL KIND OF MITOCHONDRIAL DISEASES\",\"id\":\"bienfaits\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"maxwidth\":\"large\",\"text_align\":\"left\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"center\",\"title_color\":\"primary\",\"title_element\":\"h4\",\"title_style\":\"h4\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>NAD+ participates in energy creation by acting as a delivery mechanism. This molecule donates and accepts electrons to and from enzymes in the mitochondrial membrane. It is these electrons that fuel chemical reactions in the mitochondria. Without a sufficient supply of NAD+, the mitochondria can\u2019t adequately convert the nutrients from the foods we eat into usable energy. The crucial role of NAD+ in different biological functions such as aging, metabolism, mitochondrial function, immunological pathways, oxidative stress, gene expression, and apoptosis has been extensively investigated. Many studies have found that altered and reduced NAD+ levels play an important role in stimulating metabolic disorders, neurodegenerative disorders and tumorigenesis.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"1-3\",\"width_small\":\"1-3\"},\"children\":[{\"type\":\"image\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/09\/Capture-decran-2024-09-20-a-09.20.38.png\",\"image_alt\":\"nad\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]}]}]},{\"type\":\"section\",\"props\":{\"animation\":\"slide-left-medium\",\"animation_delay\":\"200\",\"id\":\"bienfaits\",\"image_position\":\"center-center\",\"status\":\"disabled\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"small\"},\"children\":[{\"type\":\"row\",\"props\":{\"layout\":\"2-5,3-5\",\"margin_bottom\":\"remove\",\"margin_top\":\"remove\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"2-5\",\"width_small\":\"2-5\"},\"children\":[{\"type\":\"image\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/09\/Capture-decran-2024-09-20-a-09.22.34.png\",\"image_alt\":\"basic NAD+ biosynthesis pathways\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"s\",\"vertical_align\":\"middle\",\"width_medium\":\"3-5\",\"width_small\":\"3-5\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"NAD+ THERAPY HELPS DIRECTLY REPLENISH NAD+ LEVELS\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"text_align\":\"left\",\"title_element\":\"h2\",\"title_style\":\"h2\"}},{\"type\":\"headline\",\"props\":{\"content\":\"NAD+ BIOSYNTHESIS\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"text\",\"props\":{\"animation\":\"fade\",\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>To compensate for a reduction in natural NAD levels, most NAD+ is recycled via salvage pathways from nicotinamide riboside (NR), nicotinamide (NAM) and nicotinic acid (NA), which are the three main B3 vitamins that function as precursors of NAD+ (Figure 2). Each contributes to the generation of NAD+ via distinct metabolic pathways but which may be inadequate to support healthy NAD+ levels.<\/p>\n\n\\n\n\n<p>These precursors appear to have differing efficacy as primary sources of sufficient quantities of NAD+ particularly to tissues in which there is high metabolic stress and consequent high demand. Most cells and tissues utilise NR to produce NAD+, however where a deficiency exists, tryptophan catabolism through the kynurenine pathway is the sole route for de novo NAD+ synthesis and interestingly, altered kynurenine pathway activity has frequently been linked to ageing and some age-associated diseases.<\/p>\n\n\\n\n\n\n\n\\n\n\n\n\n\",\"dropcap\":false,\"margin_bottom\":\"default\",\"margin_top\":\"remove\",\"maxwidth\":\"2xlarge\",\"text_align\":\"left\",\"text_align_fallback\":\"center\"}}]}]},{\"type\":\"row\",\"props\":{\"layout\":\"3-5,2-5\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"3-5\",\"width_small\":\"3-5\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"CAN DECLINING NAD+ LEVELS BE RESTORED?\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>Low levels of NAD can be caused by a deficiency in the synthesis\/salvage pathways, excessive DNA damage due to free radicals or ultraviolet light, or chronic immune activation. Activation of PARPs in the presence of excessive or accelerated DNA damage leads to depletion of NAD.<\/p>\n\n\\n\n\n<p>When NAD levels become critically low, adenosine triphosphate (ATP) production decreases, ATP stores are utilised and eventually, cell death ensues. The increased activity of CD38 and other NAD- consuming ectoenzymes in chronic immune activation similarly depletes NAD.<\/p>\n\n\\n\n\n<p>Decreased NAD levels may be a major factor in ageing and age-related degenerative diseases of the heart, brain, liver, kidney, and skin.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"2-5\",\"width_small\":\"2-5\"},\"children\":[{\"type\":\"image\",\"props\":{\"height_expand\":false,\"image\":\"wp-content\/uploads\/2024\/09\/Capture-decran-2024-09-20-a-09.25.32-1.png\",\"image_alt\":\"NAD+ THERAPY\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]}]}],\"name\":\"Section : Les avantages\"},{\"type\":\"section\",\"props\":{\"image_position\":\"center-center\",\"status\":\"disabled\",\"style\":\"muted\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"props\":{\"layout\":\"1-3,2-3\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"1-3\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"\n\n<p><strong>Recommended daily intake of selenium for adults : Complete guide<\/strong><\/p>\n\n\",\"id\":\"apport\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"maxwidth\":\"xlarge\",\"text_align\":\"left\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"center\",\"title_color\":\"primary\",\"title_element\":\"h2\",\"title_style\":\"h2\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>Selenium intake varies according to age, sex and health conditions. In general, the recommended daily intake for adults is 55 micrograms. However, requirements may increase in cases of deficiency or certain medical conditions.<\/p>\n\n\\n\n\n<h3>Table of Recommended Selenium Intake<\/h3>\n\n\\n\n\n<p>The following table provides an estimate of suggested glutathione intakes for different age groups and conditions. It is important to note that these values may vary according to individuals and specific situations:<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"2-3\"},\"children\":[{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n\n\n\\n\n\n<table border=\\\"1\\\">\\n\n\n<tbody>\\n\n\n<tr>\\n\n\n<th>Demographic Group<\/th>\n\n\\n\n\n<th>Suggested Selenium Intake (\u00b5g\/day)<\/th>\n\n\\n\n\n<th>Specific Notes<\/th>\n\n\\n<\/tr>\n\n\\n\n\n<tr>\\n\n\n<td>Adults (Men)<\/td>\n\n\\n\n\n<td>55 \u00b5g<\/td>\n\n\\n\n\n<td>Increase in case of deficiency or specific conditions<\/td>\n\n\\n<\/tr>\n\n\\n\n\n<tr>\\n\n\n<td>Adults (Women)<\/td>\n\n\\n\n\n<td>55 \u00b5g<\/td>\n\n\\n\n\n<td>Increase during pregnancy and breastfeeding<\/td>\n\n\\n<\/tr>\n\n\\n\n\n<tr>\\n\n\n<td>Adolescents (14-18 years)<\/td>\n\n\\n\n\n<td>55 \u00b5g<\/td>\n\n\\n\n\n<td>Important for growth and development<\/td>\n\n\\n<\/tr>\n\n\\n\n\n<tr>\\n\n\n<td>Children (9-13 years)<\/td>\n\n\\n\n\n<td>40 \u00b5g<\/td>\n\n\\n\n\n<td>Essential for growth<\/td>\n\n\\n<\/tr>\n\n\\n\n\n<tr>\\n\n\n<td>Children (4-8 years)<\/td>\n\n\\n\n\n<td>30 \u00b5g<\/td>\n\n\\n\n\n<td>Essential for growth<\/td>\n\n\\n<\/tr>\n\n\\n\n\n<tr>\\n\n\n<td>Children (1-3 years)<\/td>\n\n\\n\n\n<td>20 \u00b5g<\/td>\n\n\\n\n\n<td>Essential for growth<\/td>\n\n\\n<\/tr>\n\n\\n\n\n<tr>\\n\n\n<td>Infants (0-6 months)<\/td>\n\n\\n\n\n<td>15 \u00b5g<\/td>\n\n\\n\n\n<td>Intake via breastfeeding or infant formula<\/td>\n\n\\n<\/tr>\n\n\\n\n\n<tr>\\n\n\n<td>Elderly<\/td>\n\n\\n\n\n<td>55 \u00b5g<\/td>\n\n\\n\n\n<td>Increased needs to combat inflammation and improve immunity<\/td>\n\n\\n<\/tr>\n\n\\n\n\n<tr>\\n\n\n<td>Pregnant Women<\/td>\n\n\\n\n\n<td>60 \u00b5g<\/td>\n\n\\n\n\n<td>Increased intake required<\/td>\n\n\\n<\/tr>\n\n\\n\n\n<tr>\\n\n\n<td>Breastfeeding Women<\/td>\n\n\\n\n\n<td>70 \u00b5g<\/td>\n\n\\n\n\n<td>Increased intake required to support the infant<\/td>\n\n\\n<\/tr>\n\n\\n<\/tbody>\n\n\\n<\/table>\n\n\\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"text_align\":\"center\"}}]}]}]},{\"type\":\"section\",\"props\":{\"animation\":\"fade\",\"animation_delay\":\"200\",\"image_position\":\"center-center\",\"status\":\"disabled\",\"style\":\"muted\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"Decline of NAD+ with Age\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"title_color\":\"primary\",\"title_element\":\"h2\",\"title_style\":\"h2\"}}]}]},{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"Age-related Decline and Chronic Conditions\",\"id\":\"carence\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_bottom\":\"remove\",\"margin_top\":\"remove\",\"maxwidth\":\"xlarge\",\"text_align\":\"left\",\"text_align_fallback\":\"center\",\"title_color\":\"primary\",\"title_element\":\"h3\",\"title_style\":\"h3\"}}]}]},{\"type\":\"row\",\"props\":{\"layout\":\"2-5,3-5\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"2-5\"},\"children\":[{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>NAD+ is constantly being consumed by all physical and mental functions and unfortunately, our physiological system consumes NAD+ faster than it can reproduce it once we are into our thirties.<\/p>\n\n\\n\n\n<p>The ageing process, increases chance of DNA damage, inflammation and reduced mitochondrial function which parallelly negatively affects the body's ability to produce NAD+. Emerging anecdotal and science-based evidence has implicated dysregulated NAD+ metabolism in the age-related functional decline of various tissues and organs, with lower levels of NAD+ correlated with diseases of ageing, other metabolic disorders and neurodegenerative diseases.<\/p>\n\n\\n\n\n<p>On average, NAD+ levels drop by 50% between the ages of 40 and 60 which is the scientific trigger for the decline of many basic physiological and physical functions. Therefore, therapeutically intervening and elevating NAD+ levels offers a solution for preventive health and cellular health optimisation.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"3-5\"},\"children\":[{\"type\":\"image\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/09\/Capture-decran-2024-09-20-a-09.42.25.png\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]}]},{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"WHAT CAUSES DECREASE IN NAD+?\",\"id\":\"carence\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_bottom\":\"remove\",\"margin_top\":\"remove\",\"maxwidth\":\"xlarge\",\"text_align\":\"left\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"center\",\"title_color\":\"primary\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"panel-slider\",\"props\":{\"content_column_breakpoint\":\"m\",\"content_margin\":\"small\",\"image_align\":\"top\",\"image_grid_breakpoint\":\"m\",\"image_grid_width\":\"1-2\",\"image_height\":\"200\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"image_width\":\"400\",\"link_style\":\"default\",\"link_text\":\"Read more\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"meta_align\":\"below-title\",\"meta_element\":\"div\",\"meta_style\":\"text-meta\",\"nav\":\"dotnav\",\"nav_align\":\"center\",\"nav_breakpoint\":\"\",\"panel_match\":true,\"show_content\":true,\"show_hover_image\":true,\"show_hover_video\":true,\"show_image\":true,\"show_link\":true,\"show_meta\":true,\"show_title\":true,\"show_video\":true,\"slidenav\":\"outside\",\"slidenav_breakpoint\":\"\",\"slidenav_margin\":\"small\",\"slidenav_outside_breakpoint\":\"xl\",\"slider_autoplay_pause\":true,\"slider_gap\":\"default\",\"slider_width\":\"fixed\",\"slider_width_default\":\"5-6\",\"slider_width_medium\":\"1-3\",\"slider_width_small\":\"1-4\",\"text_align\":\"center\",\"title_align\":\"top\",\"title_element\":\"h3\",\"title_grid_breakpoint\":\"m\",\"title_grid_width\":\"1-2\",\"title_hover_style\":\"reset\",\"title_style\":\"h5\"},\"children\":[{\"type\":\"panel-slider_item\",\"props\":{\"content\":\"Various lifestyle choices might negatively\\ninfluence our NAD+ levels such as stress,\\npoor diet, irregular working-life-balance\\nand reduced or poor quality sleep.\",\"image\":\"wp-content\/uploads\/2024\/09\/1.png\",\"title\":\"LIFESTYLE CHOICES\"}},{\"type\":\"panel-slider_item\",\"props\":{\"content\":\"Excessive alcohol, nicotine, recreational\\ndrugs, prescribed medication or other\\nsubstances decrease NAD+ levels.\",\"image\":\"wp-content\/uploads\/2024\/09\/2.png\",\"title\":\"SUBSTANCE ABUSE\"}},{\"type\":\"panel-slider_item\",\"props\":{\"content\":\"Ageing is most commonly associated with\\ndecreased levels of NAD+. Levels decline by\\nhalf by the time a human is middle aged, with\\nimplications for combating age-related\\nconditions and diseases.\",\"image\":\"wp-content\/uploads\/2024\/09\/3.png\",\"image_alt\":\"ageing\",\"title\":\"AGEING\"}},{\"type\":\"panel-slider_item\",\"props\":{\"content\":\"Chronic illness is typically a result of\\nmitochondrial dysfunction, which can be\\ntriggered by decreased NAD+ levels.\",\"image\":\"wp-content\/uploads\/2024\/09\/4-1.png\",\"image_alt\":\"chronic diseases\",\"title\":\"CHRONIC DISEASES\"}}]}]}]}]},{\"type\":\"section\",\"props\":{\"animation\":\"fade\",\"animation_delay\":\"200\",\"image_position\":\"center-center\",\"status\":\"disabled\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"NAD+ Therapy\",\"css\":\".el-element {\\n    text-transform : uppercase;}\",\"id\":\"iv\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_bottom\":\"large\",\"margin_top\":\"remove\",\"text_align\":\"center\",\"title_color\":\"primary\",\"title_element\":\"h2\",\"title_style\":\"h2\"}}]}]},{\"type\":\"row\",\"props\":{\"layout\":\"1-2,1-2\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"1-2\",\"width_small\":\"1-2\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"How NAD+ Therapy Works ?\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"NAD+ therapy works by replenishing NAD+ levels, improving mitochondrial health, and enhancing cellular repair mechanisms. It helps restore the balance in energy metabolism and cellular function.\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"1-2\",\"width_small\":\"1-2\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"NAD+ IV Therapy\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"Intravenous (IV) NAD+ therapy is the most effective way to increase NAD+ levels quickly. The therapy delivers NAD+ directly into the bloodstream, providing significant benefits for brain function, energy levels, and overall performance.\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]}]},{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"Nad+ IV is typically used for the following reasons : \",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"title_element\":\"h3\",\"title_style\":\"h3\"}},{\"type\":\"grid\",\"props\":{\"content_column_breakpoint\":\"m\",\"css\":\".el-item {\\n    border-radius : 20px;}\",\"filter_align\":\"left\",\"filter_all\":true,\"filter_grid_breakpoint\":\"m\",\"filter_grid_width\":\"auto\",\"filter_position\":\"top\",\"filter_style\":\"tab\",\"grid_default\":\"1\",\"grid_medium\":\"4\",\"grid_small\":\"4\",\"image_align\":\"top\",\"image_grid_breakpoint\":\"m\",\"image_grid_width\":\"1-2\",\"image_svg_color\":\"emphasis\",\"item_animation\":true,\"lightbox_bg_close\":true,\"link_style\":\"default\",\"link_text\":\"Read more\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"meta_align\":\"below-title\",\"meta_element\":\"div\",\"meta_style\":\"text-meta\",\"panel_padding\":\"small\",\"panel_style\":\"card-primary\",\"show_content\":true,\"show_hover_image\":true,\"show_hover_video\":true,\"show_image\":true,\"show_link\":false,\"show_meta\":true,\"show_title\":true,\"show_video\":true,\"text_align\":\"center\",\"title_align\":\"top\",\"title_element\":\"h3\",\"title_grid_breakpoint\":\"m\",\"title_grid_width\":\"1-2\",\"title_hover_style\":\"reset\",\"title_style\":\"text-meta\"},\"children\":[{\"type\":\"grid_item\",\"props\":{\"title\":\"Improving Metabolsim\"}},{\"type\":\"grid_item\",\"props\":{\"title\":\"Addressing Chronic Fatigue\"}},{\"type\":\"grid_item\",\"props\":{\"title\":\"Combatting Ageing\"}},{\"type\":\"grid_item\",\"props\":{\"title\":\"Fighting Chronic Conditions\"}},{\"type\":\"grid_item\",\"props\":{\"title\":\"Improving Concentration & Focus\"}},{\"type\":\"grid_item\",\"props\":{\"title\":\"Relieving Burnout & Stress\"}},{\"type\":\"grid_item\",\"props\":{\"title\":\"Lifestyle Detoxing\"}},{\"type\":\"grid_item\",\"props\":{\"title\":\"Increasing Fertility Levels\"}}]}]}]}]},{\"type\":\"section\",\"props\":{\"animation\":\"fade\",\"animation_delay\":\"200\",\"image_position\":\"center-center\",\"status\":\"disabled\",\"style\":\"muted\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"small\"},\"children\":[{\"type\":\"row\",\"props\":{\"layout\":\"2-5,3-5\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"2-5\",\"width_small\":\"2-5\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"NAD+ IV solution\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_top\":\"remove\",\"title_element\":\"h3\",\"title_style\":\"h2\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>YuBoost produces and supplies NAD+IV as an intravenous solution, the most effective and efficient way of increasing the body's own NAD+ levels. Studies prove that restoring levels of NAD+ in your cells has benefits for your brain and body, helping repair DNA, protect brain cells from damage, reduce inflammation and prevent ageing.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}},{\"type\":\"button\",\"props\":{\"grid_column_gap\":\"small\",\"grid_row_gap\":\"small\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"},\"children\":[{\"type\":\"button_item\",\"props\":{\"button_style\":\"danger\",\"content\":\"Book your NAD+ IV\",\"dialog_layout\":\"modal\",\"dialog_offcanvas_flip\":true,\"icon_align\":\"left\",\"link\":\"en\/booking\/\"}}]}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"3-5\",\"width_small\":\"2-3\"},\"children\":[{\"name\":\"Panel Slider th\u00e9rapies VF 3\",\"type\":\"panel-slider\",\"children\":[{\"type\":\"panel-slider_item\",\"props\":{\"content\":\"\n\n<p 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articles<\/strong><\/p>\n\n\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_bottom\":\"remove\",\"margin_top\":\"remove\",\"title_color\":\"primary\",\"title_element\":\"h2\",\"title_style\":\"h2\"}},{\"type\":\"panel-slider\",\"props\":{\"content_column_breakpoint\":\"m\",\"image_align\":\"left\",\"image_grid_breakpoint\":\"\",\"image_grid_width\":\"2-5\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"link_style\":\"text\",\"link_text\":\"\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"meta_align\":\"below-title\",\"meta_element\":\"div\",\"meta_style\":\"text-meta\",\"nav\":\"dotnav\",\"nav_align\":\"center\",\"nav_breakpoint\":\"\",\"panel_image_no_padding\":false,\"panel_link\":true,\"panel_match\":true,\"panel_padding\":\"small\",\"show_content\":true,\"show_hover_image\":true,\"show_hover_video\":true,\"show_image\":true,\"show_link\":true,\"show_meta\":true,\"show_title\":true,\"show_video\":true,\"slidenav\":\"outside\",\"slidenav_breakpoint\":\"\",\"slidenav_margin\":\"medium\",\"slidenav_outside_breakpoint\":\"xl\",\"slider_autoplay_pause\":true,\"slider_gap\":\"default\",\"slider_width\":\"fixed\",\"slider_width_default\":\"5-6\",\"slider_width_medium\":\"4-5\",\"slider_width_small\":\"4-5\",\"title_align\":\"top\",\"title_color\":\"emphasis\",\"title_element\":\"div\",\"title_grid_breakpoint\":\"m\",\"title_grid_width\":\"1-2\",\"title_hover_style\":\"reset\",\"title_link\":true,\"title_style\":\"text-meta\"},\"children\":[{\"type\":\"panel-slider_item\",\"source\":{\"props\":{\"title\":{\"filters\":{\"search\":\"\"},\"name\":\"title\"},\"image\":{\"filters\":{\"search\":\"\"},\"name\":\"featuredImage.url\"},\"link\":{\"filters\":{\"search\":\"\"},\"name\":\"link\"}},\"query\":{\"name\":\"pages.customPage\",\"arguments\":{\"users\":[],\"users_operator\":\"IN\",\"offset\":0,\"order\":\"date\",\"order_direction\":\"DESC\",\"id\":31755}}}}]}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"3-5\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"\n\n<p><strong>Discover other vitamins<\/strong><\/p>\n\n\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_bottom\":\"remove\",\"margin_top\":\"remove\",\"title_color\":\"primary\",\"title_element\":\"h2\",\"title_style\":\"h2\"}},{\"type\":\"panel-slider\",\"props\":{\"content_column_breakpoint\":\"m\",\"image_align\":\"left\",\"image_grid_breakpoint\":\"\",\"image_grid_width\":\"auto\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"image_transition\":\"scale-up\",\"link_style\":\"text\",\"link_text\":\"\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"meta_align\":\"below-title\",\"meta_element\":\"div\",\"meta_style\":\"text-meta\",\"nav\":\"dotnav\",\"nav_align\":\"center\",\"nav_breakpoint\":\"\",\"panel_image_no_padding\":false,\"panel_link\":true,\"panel_match\":true,\"panel_padding\":\"small\",\"show_content\":false,\"show_hover_image\":true,\"show_hover_video\":true,\"show_image\":true,\"show_link\":true,\"show_meta\":false,\"show_title\":false,\"show_video\":true,\"slidenav\":\"outside\",\"slidenav_breakpoint\":\"\",\"slidenav_margin\":\"medium\",\"slidenav_outside_breakpoint\":\"xl\",\"slider_autoplay_pause\":true,\"slider_gap\":\"default\",\"slider_width\":\"fixed\",\"slider_width_default\":\"5-6\",\"slider_width_medium\":\"1-3\",\"slider_width_small\":\"1-3\",\"title_align\":\"top\",\"title_color\":\"emphasis\",\"title_element\":\"div\",\"title_grid_breakpoint\":\"m\",\"title_grid_width\":\"1-2\",\"title_hover_style\":\"reset\",\"title_link\":true,\"title_style\":\"text-meta\"},\"children\":[{\"type\":\"panel-slider_item\",\"source\":{\"props\":{\"title\":{\"filters\":{\"search\":\"\"},\"name\":\"title\"},\"image\":{\"filters\":{\"search\":\"\"},\"name\":\"featuredImage.url\"},\"link\":{\"filters\":{\"search\":\"\"},\"name\":\"link\"}},\"query\":{\"name\":\"posts.customPost\",\"arguments\":{\"terms\":[48],\"category_operator\":\"IN\",\"post_tag_operator\":\"IN\",\"users\":[],\"users_operator\":\"IN\",\"offset\":0,\"order\":\"date\",\"order_direction\":\"DESC\",\"id\":30485}}}},{\"type\":\"panel-slider_item\",\"source\":{\"props\":{\"title\":{\"filters\":{\"search\":\"\"},\"name\":\"title\"},\"image\":{\"filters\":{\"search\":\"\"},\"name\":\"featuredImage.url\"},\"link\":{\"filters\":{\"search\":\"\"},\"name\":\"link\"}},\"query\":{\"name\":\"posts.customPost\",\"arguments\":{\"terms\":[48],\"category_operator\":\"IN\",\"post_tag_operator\":\"IN\",\"users\":[],\"users_operator\":\"IN\",\"offset\":0,\"order\":\"date\",\"order_direction\":\"DESC\",\"id\":31512}}}},{\"type\":\"panel-slider_item\",\"source\":{\"props\":{\"title\":{\"filters\":{\"search\":\"\"},\"name\":\"title\"},\"image\":{\"filters\":{\"search\":\"\"},\"name\":\"featuredImage.url\"},\"link\":{\"filters\":{\"search\":\"\"},\"name\":\"link\"}},\"query\":{\"name\":\"posts.customPost\",\"arguments\":{\"terms\":[48],\"category_operator\":\"IN\",\"post_tag_operator\":\"IN\",\"users\":[],\"users_operator\":\"IN\",\"offset\":0,\"order\":\"date\",\"order_direction\":\"DESC\",\"id\":30425}}}},{\"type\":\"panel-slider_item\",\"source\":{\"props\":{\"title\":{\"filters\":{\"search\":\"\"},\"name\":\"title\"},\"image\":{\"filters\":{\"search\":\"\"},\"name\":\"featuredImage.url\"},\"link\":{\"filters\":{\"search\":\"\"},\"name\":\"link\"}},\"query\":{\"name\":\"posts.customPost\",\"arguments\":{\"terms\":[48],\"category_operator\":\"IN\",\"post_tag_operator\":\"IN\",\"users\":[],\"users_operator\":\"IN\",\"offset\":0,\"order\":\"date\",\"order_direction\":\"DESC\",\"id\":30492}}}},{\"type\":\"panel-slider_item\",\"source\":{\"props\":{\"title\":{\"filters\":{\"search\":\"\"},\"name\":\"title\"},\"image\":{\"filters\":{\"search\":\"\"},\"name\":\"featuredImage.url\"},\"link\":{\"filters\":{\"search\":\"\"},\"name\":\"link\"}},\"query\":{\"name\":\"posts.customPost\",\"arguments\":{\"terms\":[48],\"category_operator\":\"IN\",\"post_tag_operator\":\"IN\",\"users\":[],\"users_operator\":\"IN\",\"offset\":0,\"order\":\"date\",\"order_direction\":\"DESC\",\"id\":31513}}}},{\"type\":\"panel-slider_item\",\"source\":{\"props\":{\"title\":{\"filters\":{\"search\":\"\"},\"name\":\"title\"},\"image\":{\"filters\":{\"search\":\"\"},\"name\":\"featuredImage.url\"},\"link\":{\"filters\":{\"search\":\"\"},\"name\":\"link\"}},\"query\":{\"name\":\"posts.customPost\",\"arguments\":{\"terms\":[48],\"category_operator\":\"IN\",\"post_tag_operator\":\"IN\",\"users\":[],\"users_operator\":\"IN\",\"offset\":0,\"order\":\"date\",\"order_direction\":\"DESC\",\"id\":30494}}}}]}]}],\"props\":{\"layout\":\"2-5,3-5\"}}]},{\"type\":\"section\",\"props\":{\"image_position\":\"center-center\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"middle\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"props\":{\"layout\":\"1-2,1-2\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"style\":\"card-default\",\"width_large\":\"1-2\",\"width_medium\":\"1-2\",\"width_small\":\"1-1\"},\"children\":[{\"type\":\"panel\",\"props\":{\"class\":\"cardyuboost1\",\"content\":\"\",\"content_column_breakpoint\":\"m\",\"css\":\".el-image {\\n    padding:20px;}\",\"height_expand\":false,\"image\":\"wp-content\/uploads\/2025\/07\/NAD.png\",\"image_align\":\"top\",\"image_alt\":\"nad+\",\"image_grid_breakpoint\":\"m\",\"image_grid_width\":\"1-2\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"link_style\":\"default\",\"link_text\":\"Read more\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"meta_align\":\"below-title\",\"meta_element\":\"div\",\"meta_style\":\"text-meta\",\"title_align\":\"top\",\"title_element\":\"h3\",\"title_grid_breakpoint\":\"m\",\"title_grid_width\":\"1-2\",\"title_hover_style\":\"reset\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_large\":\"1-2\",\"width_medium\":\"1-2\",\"width_small\":\"1-1\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"NAD+: definition, role, benefits, and link to longevity\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"title_element\":\"h1\"}},{\"type\":\"breadcrumbs\",\"props\":{\"show_current\":false,\"show_home\":true}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p><strong>NAD+<\/strong> is a <strong>vital<\/strong> coenzyme found in all our cells. It supports <strong>energy production<\/strong>, <strong>DNA repair<\/strong>, <strong>mitochondrial function<\/strong>, and contributes to <strong>healthy aging<\/strong>.<\/p>\n\n \n\n<p>As we age, its levels decline, which can result in fatigue, cognitive decline, and increased vulnerability to chronic diseases.<\/p>\n\n \n\n<p>Discover our page on <a href=\\\"https:\/\/yuboost.com\/en\/iv-therapy\/nad\/\/\\\">NAD+ therapies (IV Therapy)<\/a>, available at home in Switzerland.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}},{\"type\":\"text\",\"props\":{\"block_align\":\"center\",\"column_breakpoint\":\"m\",\"content\":\"\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"maxwidth\":\"xlarge\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<h2 class=\\\"uk-h5\\\">Table of Contents<\/h2>\n\n\\n\n\n<ul class=\\\"uk-list uk-list-decimal uk-margin-remove\\\">\\n  \n\n<li><a href=\\\"#definition\\\">What is NAD+?<\/a><\/li>\n\n\\n  \n\n<li><a href=\\\"#roles\\\">The physiological roles of NAD+<\/a><\/li>\n\n\\n  \n\n<li><a href=\\\"#bienfaits\\\">The benefits of NAD+ in humans<\/a><\/li>\n\n\\n  \n\n<li><a href=\\\"#declins\\\">NAD+ decline with age<\/a><\/li>\n\n\\n  \n\n<li><a href=\\\"#longevite\\\">NAD+ and longevity: what science says<\/a><\/li>\n\n\\n  \n\n<li><a href=\\\"#solutions\\\">Our Yuboost solutions<\/a><\/li>\n\n\\n  \n\n<li><a href=\\\"#faq\\\">FAQ \u2013 NAD+<\/a><\/li>\n\n\\n<\/ul>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]}]}]},{\"type\":\"section\",\"props\":{\"id\":\"definition\",\"image_position\":\"center-center\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"middle\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"class\":\"cardyuboost1\",\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"style\":\"card-default\",\"vertical_align\":\"middle\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"What is NAD+ ?\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"text_align\":\"center\",\"text_align_fallback\":\"center\",\"title_element\":\"h2\",\"title_style\":\"h2\"}},{\"type\":\"text\",\"props\":{\"block_align\":\"center\",\"column_breakpoint\":\"m\",\"content\":\"\n\n<p style=\\\"text-align: left;\\\">NAD+ (<em>nicotinamide adenine dinucleotide<\/em>) is a universal coenzyme involved in hundreds of metabolic reactions. Without NAD+, <strong>ATP<\/strong> production and cellular homeostasis cannot be maintained.<\/p>\n\n\\n\\n\n\n<p style=\\\"text-align: left;\\\"><strong>Key mechanisms<\/strong>:<\/p>\n\n\\n\\n\n\n<ul style=\\\"text-align: left;\\\">\\n\n\n<li style=\\\"text-align: left;\\\"><strong>Electron transport<\/strong> in cellular respiration (NAD+ \u2192 NADH), essential for oxidative phosphorylation and ATP synthesis.<\/li>\n\n\\n\n\n<li style=\\\"text-align: left;\\\"><strong>Longevity regulation<\/strong>: substrate for <strong>sirtuins<\/strong> (gene expression, cellular stress response) and <strong>PARP<\/strong> (DNA repair).<\/li>\n\n\\n\n\n<li style=\\\"text-align: left;\\\"><strong>Immune signaling<\/strong> via <strong>CD38<\/strong> and maintenance of mitochondrial redox balance.<\/li>\n\n\\n<\/ul>\n\n\\n\\n\n\n<p style=\\\"text-align: left;\\\">In practice, NAD+ directly connects energy metabolism, cellular repair, and resistance to aging.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"maxwidth\":\"2xlarge\",\"text_align\":\"center\"}}]}],\"props\":{\"width\":\"small\"}}],\"name\":\"D\u00e9finition\"},{\"type\":\"section\",\"props\":{\"css\":\".el-section {\\n    padding : 20px;}\",\"id\":\"roles\",\"image_position\":\"center-center\",\"overlap\":false,\"padding_bottom\":\"small\",\"padding_top\":\"small\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"small\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"The physiological roles of NAD+\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"text_align\":\"center\",\"text_align_fallback\":\"center\",\"title_color\":\"success\",\"title_element\":\"h2\",\"title_style\":\"h2\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>Beyond its definition, NAD+ is involved in essential cellular mechanisms that determine our health and longevity.<\/p>\n\n\\n\\n\n\n<p>A sustained imbalance in NAD+ metabolism can disrupt physiological functions and lead to diseases such as metabolic disorders, cancer, premature aging, and neurodegenerative conditions.<\/p>\n\n\\n\\n\n\n<p>Here are the main areas where its action is critical:<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"text_align\":\"center\"}}]}]},{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"1-2\"},\"children\":[{\"type\":\"accordion\",\"props\":{\"collapsible\":true,\"content_column_breakpoint\":\"m\",\"css\":\".el-title {\\n    font-size : 14px;}\",\"image_align\":\"top\",\"image_grid_breakpoint\":\"m\",\"image_grid_width\":\"1-2\",\"image_svg_color\":\"emphasis\",\"link_style\":\"default\",\"link_text\":\"Read more\",\"show_image\":true,\"show_link\":true},\"children\":[{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>\\n    NAD+ acts as a cellular \\\"battery.\\\" It captures and transports electrons during metabolic reactions,\\n    enabling the production of <strong>ATP<\/strong>, the body's primary energy source.\\n<\/p>\n\n\\n\n\n<p>\\n    During glycolysis and the Krebs cycle, NAD+ is reduced to NADH, which then feeds the mitochondrial\\n    respiratory chain and oxidative phosphorylation. This process results in the synthesis of large amounts of ATP.\\n<\/p>\n\n\",\"title\":\"\n\n<h3>Cellular energy production (ATP)<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>\\n    NAD+ is essential for <strong>DNA repair<\/strong>. It serves as a substrate for PARP, an enzyme\\n    activated during DNA breaks. At the same time, it activates <strong>sirtuins<\/strong>, which regulate\\n    gene expression and contribute to longevity mechanisms.\\n<\/p>\n\n\\n\n\n<p>\\n    Low levels of NAD+ lead to an accumulation of genetic damage, promoting premature aging, cancer,\\n    and degenerative diseases.\\n<\/p>\n\n\",\"title\":\"\n\n<h3>DNA repair and protection<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>\\n    The <strong>mitochondria<\/strong> are the \\\"powerhouses\\\" of our cells. NAD+ acts directly by supporting\\n    cellular respiration and regulating oxidative stress.\\n<\/p>\n\n\\n\n\n<p>\\n    Studies show that increasing NAD+ stimulates <strong>mitochondrial biogenesis<\/strong> and activates\\n    protective pathways such as <strong>PGC1\u03b1<\/strong> and sirtuins.\\n<\/p>\n\n\",\"title\":\"\n\n<h3>Mitochondrial function and oxidative stress<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>\\n    NAD+ also plays a role in <strong>immune signaling<\/strong> and the proper functioning of the nervous system.\\n    It influences neurotransmitter release and helps protect neurons against oxidative stress.\\n<\/p>\n\n\",\"title\":\"\n\n<h3>Immune function and neuroprotection<\/h3>\n\n\"}}]}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"1-2\"},\"children\":[{\"type\":\"image\",\"props\":{\"height_expand\":true,\"image\":\"wp-content\/uploads\/2025\/09\/NAD_phys.svg\",\"image_alt\":\"nad+\",\"image_height\":250,\"image_svg_color\":\"emphasis\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"position\":\"relative\",\"position_left\":\"100\",\"text_align\":\"right\",\"visibility\":\"s\"}}]}],\"props\":{\"layout\":\"1-2,1-2\",\"margin_bottom\":\"medium\",\"margin_top\":\"medium\"}}],\"name\":\"R\u00f4les Physiologiques\"},{\"type\":\"section\",\"props\":{\"id\":\"bienfaits\",\"image_position\":\"center-center\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"middle\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"The benefits of NAD+ in 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neuronales\",\"title\":\"Improves memory, concentration and mental clarity\"}},{\"type\":\"panel-slider_item\",\"props\":{\"image\":\"wp-content\/uploads\/2025\/03\/cellulaire.png\",\"image_alt\":\"connexion neuronales\",\"title\":\"Contributes to slowing down cellular aging\"}},{\"type\":\"panel-slider_item\",\"props\":{\"image\":\"wp-content\/uploads\/2025\/04\/antidepresseur.png\",\"image_alt\":\"anti depresseur\",\"status\":\"disabled\",\"title\":\"Supports mental clarity and focus, especially during cognitive fatigue or mental overload\"}},{\"type\":\"panel-slider_item\",\"props\":{\"image\":\"wp-content\/uploads\/2024\/12\/8.png\",\"image_alt\":\"anti depresseur\",\"title\":\"Promotes physical recovery after sports, stress or burnout\"}},{\"type\":\"panel-slider_item\",\"props\":{\"image\":\"wp-content\/uploads\/2025\/04\/perfomance-athletique.png\",\"image_alt\":\"perfomance athletique\",\"title\":\"Increases endurance\"}}]}]}],\"props\":{\"class\":\"cardyuboost1\"}}],\"name\":\"Bienfaits\"},{\"type\":\"section\",\"props\":{\"id\":\"declin\",\"image_position\":\"center-center\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"middle\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"Decline in NAD+ with age\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_bottom\":\"remove\",\"margin_top\":\"remove\",\"text_align\":\"center\",\"text_align_fallback\":\"center\",\"title_element\":\"h2\",\"title_style\":\"h2\"}}]}],\"props\":{\"margin_bottom\":\"large\",\"margin_top\":\"large\"}},{\"type\":\"row\",\"props\":{\"layout\":\"1-2,1-2\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"width_medium\":\"1-2\"},\"children\":[{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>NAD+ is constantly consumed by all physical and mental functions, and unfortunately, our physiological system uses up NAD+ faster than it can be replenished once we reach our thirties.<\/p>\n\n\\n\n\n<p>The aging process increases the risk of DNA damage, inflammation, and reduced mitochondrial function, which in turn negatively affects the body's ability to produce NAD+.<\/p>\n\n\\n\n\n<p>On average, <strong>NAD+ levels drop by 50% between ages 40 and 60,<\/strong> representing the scientific trigger for the decline of many basic physiological and physical functions.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\"}}]},{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"vertical_align\":\"middle\",\"width_medium\":\"1-2\"},\"children\":[{\"type\":\"image\",\"props\":{\"css\":\".el-image {\\n    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  border-radius : 20px;}\",\"image_align\":\"top\",\"image_grid_breakpoint\":\"m\",\"image_grid_width\":\"1-2\",\"image_height\":\"200\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"image_width\":\"400\",\"link_style\":\"default\",\"link_text\":\"Read more\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"meta_align\":\"below-title\",\"meta_element\":\"div\",\"meta_style\":\"text-meta\",\"nav\":\"dotnav\",\"nav_align\":\"center\",\"nav_breakpoint\":\"\",\"panel_match\":true,\"show_content\":true,\"show_hover_image\":true,\"show_hover_video\":true,\"show_image\":true,\"show_link\":true,\"show_meta\":true,\"show_title\":true,\"show_video\":true,\"slidenav\":\"outside\",\"slidenav_breakpoint\":\"\",\"slidenav_margin\":\"small\",\"slidenav_outside_breakpoint\":\"xl\",\"slider_autoplay_pause\":true,\"slider_gap\":\"default\",\"slider_width\":\"fixed\",\"slider_width_default\":\"5-6\",\"slider_width_medium\":\"1-3\",\"slider_width_small\":\"1-4\",\"text_align\":\"center\",\"title_align\":\"top\",\"title_element\":\"h3\",\"title_grid_breakpoint\":\"m\",\"title_grid_width\":\"1-2\",\"title_hover_style\":\"reset\",\"title_style\":\"h5\"},\"children\":[{\"type\":\"panel-slider_item\",\"props\":{\"content\":\"\n\n<p>Various lifestyle choices can negatively impact our NAD+ levels, such as stress, poor nutrition, an imbalanced work-life schedule, and reduced or poor-quality sleep.<\/p>\n\n\",\"image\":\"wp-content\/uploads\/2024\/09\/1.png\",\"title\":\"Lifestyle choices\"}},{\"type\":\"panel-slider_item\",\"props\":{\"content\":\"\n\n<p>Excessive alcohol, nicotine, recreational drugs, prescription medications, or other substances reduce NAD+ levels.<\/p>\n\n\",\"image\":\"wp-content\/uploads\/2024\/09\/2.png\",\"title\":\"Substance abus\"}},{\"type\":\"panel-slider_item\",\"props\":{\"content\":\"\n\n<p>Aging is most often associated with a decrease in NAD+ levels. Levels drop by half by middle age, which impacts the body\u2019s ability to combat age-related conditions and diseases.<\/p>\n\n\",\"image\":\"wp-content\/uploads\/2024\/09\/3.png\",\"image_alt\":\"ageing\",\"title\":\"Aging\"}},{\"type\":\"panel-slider_item\",\"props\":{\"content\":\"\n\n<p>Chronic diseases are generally the result of mitochondrial dysfunction, which can be triggered by a decrease in NAD+ levels.<\/p>\n\n\",\"image\":\"wp-content\/uploads\/2024\/09\/4-1.png\",\"image_alt\":\"chronic diseases\",\"title\":\"Chronic diseases\"}}],\"name\":\"Panel : D\u00e9clin du NAD\"}]}]}],\"name\":\"D\u00e9clin\"},{\"type\":\"section\",\"props\":{\"image_position\":\"center-center\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"middle\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"How to increase your NAD+ levels?\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"text_align\":\"center\",\"text_align_fallback\":\"center\",\"title_element\":\"h3\",\"title_style\":\"h2\"}},{\"type\":\"grid\",\"props\":{\"class\":\"cardyuboost\",\"content_column_breakpoint\":\"m\",\"filter_align\":\"left\",\"filter_all\":true,\"filter_grid_breakpoint\":\"m\",\"filter_grid_width\":\"auto\",\"filter_position\":\"top\",\"filter_style\":\"tab\",\"grid_default\":\"1\",\"grid_large\":\"3\",\"grid_medium\":\"2\",\"grid_small\":\"2\",\"image_align\":\"top\",\"image_grid_breakpoint\":\"m\",\"image_grid_width\":\"1-2\",\"image_svg_color\":\"emphasis\",\"image_width\":80,\"item_animation\":true,\"lightbox_bg_close\":true,\"link_style\":\"default\",\"link_text\":\"Read more\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"meta_align\":\"below-title\",\"meta_element\":\"div\",\"meta_style\":\"text-meta\",\"show_content\":true,\"show_hover_image\":true,\"show_hover_video\":true,\"show_image\":true,\"show_link\":true,\"show_meta\":true,\"show_title\":true,\"show_video\":true,\"title_align\":\"top\",\"title_color\":\"success\",\"title_element\":\"h3\",\"title_font_family\":\"secondary\",\"title_grid_breakpoint\":\"m\",\"title_grid_width\":\"1-2\",\"title_hover_style\":\"reset\",\"title_style\":\"h3\"},\"children\":[{\"type\":\"grid_item\",\"props\":{\"content\":\"\n\n<ul>\\n  \n\n<li>Diet rich in vitamin B3 (niacin, tryptophan).<\/li>\n\n\\n  \n\n<li>Regular physical activity.<\/li>\n\n\\n  \n\n<li>Restorative sleep.<\/li>\n\n\\n  \n\n<li>Stress management and a balanced lifestyle.<\/li>\n\n\\n<\/ul>\n\n\",\"image\":\"\",\"image_alt\":\"detox\",\"title\":\"<img src=\\\"\/wp-content\/uploads\/2025\/04\/65.png\\\" alt=\\\"icon\\\" width=\\\"50\\\" style=\\\"margin-right:6px; vertical-align:middle;\\\"> Natural solutions\"}},{\"type\":\"grid_item\",\"props\":{\"content\":\"\n\n<p>\\n  NAD+ precursors such as <strong>nicotinamide riboside (NR)<\/strong> and\\n  <strong>nicotinamide mononucleotide (NMN)<\/strong> are the subject of numerous studies.\\n  They appear promising for supporting NAD+ levels, but research is still ongoing.\\n<\/p>\n\n\",\"title\":\"<img src=\\\"https:\/\/yuboost.com\/wp-content\/uploads\/2025\/04\/vitamines-a-domicile.png\\\" alt=\\\"icon\\\" width=\\\"50\\\" style=\\\"margin-right:6px; vertical-align:middle;\\\"> Supplements and research\"}},{\"type\":\"grid_item\",\"props\":{\"content\":\"\n\n<p>\\n  <strong>NAD+ therapy<\/strong> via intravenous infusion is the most effective way to quickly boost NAD+ levels. \\n  It delivers NAD+ directly into the bloodstream, providing significant benefits for brain function, energy levels, and overall performance.\\n  <a href=\\\"https:\/\/yuboost.com\/en\/iv-therapy\/nad\/\/\\\">NAD+ IV Therapy<\/a>.\\n<\/p>\n\n\",\"title\":\"<img src=\\\"https:\/\/yuboost.com\/wp-content\/uploads\/2025\/09\/ICONE-YUBOOST.png\\\" alt=\\\"icon\\\" width=\\\"50\\\" style=\\\"margin-right:6px; vertical-align:middle;\\\"> NAD+ infusion\"}}]}]}]}]},{\"type\":\"section\",\"props\":{\"css\":\".el-section {\\n\\tpadding : 20px;}\",\"id\":\"longevite\",\"image_position\":\"center-center\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"props\":{\"width\":\"xsmall\"},\"children\":[{\"type\":\"column\",\"props\":{\"class\":\"cardyuboost1\",\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\",\"style\":\"card-default\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"NAD+ and longevity: what science says\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"text_align\":\"center\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"left\",\"title_color\":\"success\",\"title_element\":\"h2\",\"title_style\":\"h2\"}},{\"type\":\"text\",\"props\":{\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>NAD+ is directly linked to aging mechanisms.<\/p>\n\n\\n\n\n<p>Its gradual decline leads to impaired mitochondrial function, reduced DNA repair, and dysregulation of gene expression\u2014all factors that accelerate cellular decline.<\/p>\n\n\\n\n\n<p>Numerous studies confirm its central role in longevity.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"text_align\":\"center\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"left\"}},{\"type\":\"accordion\",\"props\":{\"collapsible\":true,\"content_column_breakpoint\":\"m\",\"css\":\".el-title {\\n    font-size : 14px;}\",\"image_align\":\"top\",\"image_grid_breakpoint\":\"m\",\"image_grid_width\":\"1-2\",\"image_svg_color\":\"emphasis\",\"link_style\":\"default\",\"link_text\":\"Read more\",\"multiple\":true,\"show_image\":true,\"show_link\":true},\"children\":[{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>\u279d Shows the role of NAD+ in activating sirtuins, proteins involved in longevity and aging regulation.<\/p>\n\n\\n\n\n<p><strong>Associated study:<\/strong> <a href=\\\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23454760\/\\\">PubMed<\/a><\/p>\n\n\",\"title\":\"NAD+ and sirtuins in aging and disease\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>\u279d Describes how the decline of NAD+ with age disrupts communication between the nucleus and mitochondria, accelerating aging.<\/p>\n\n\\n\n\n<p><strong>Associated study:<\/strong> <a href=\\\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24360282\/\\\">PubMed \u2013 24360282<\/a><\/p>\n\n\",\"title\":\"Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>\u279d Comprehensive review of the link between NAD+, aging, and age-related diseases (neurodegenerative, metabolic, cardiovascular).<\/p>\n\n\\n\n\n<p><strong>Associated study:<\/strong> <a href=\\\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29779976\/\\\">PubMed \u2013 29779976<\/a><\/p>\n\n\",\"title\":\"NAD+ and redox metabolism in aging and disease\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>\u279d Highlights the importance of NAD+ in protecting against age-related neurodegenerative diseases.<\/p>\n\n\\n\n\n<p><strong>Associated study:<\/strong> <a href=\\\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30586782\/\\\">PubMed \u2013 30586782<\/a><\/p>\n\n\",\"title\":\"NAD+ in aging, metabolism, and neurodegeneration\"}}]}]}]}],\"name\":\"NAD+ et long\u00e9vit\u00e9 : ce que dit la science\"},{\"type\":\"section\",\"props\":{\"css\":\".el-section {\\n    padding : 20px;}\",\"id\":\"mecanismes\",\"image_position\":\"center-center\",\"overlap\":false,\"padding_bottom\":\"small\",\"padding_top\":\"small\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"small\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"The scientific mechanisms of NAD+\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"text_align\":\"center\",\"text_align_fallback\":\"center\",\"title_color\":\"success\",\"title_element\":\"h2\",\"title_style\":\"h2\"}},{\"type\":\"accordion\",\"props\":{\"collapsible\":true,\"content_column_breakpoint\":\"m\",\"css\":\".el-title {\\n    font-size : 14px;}\",\"image_align\":\"top\",\"image_grid_breakpoint\":\"m\",\"image_grid_width\":\"1-2\",\"image_svg_color\":\"emphasis\",\"link_style\":\"default\",\"link_text\":\"Read more\",\"multiple\":true,\"show_image\":true,\"show_link\":true},\"children\":[{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>Glycolysis is the first step in cellular energy production.<br \/>NAD+ acts as an electron acceptor during the breakdown of glucose into pyruvate, producing NADH that will then feed mitochondrial respiration.<\/p>\n\n\\n\n\n<p>\ud83d\udd2c <strong>Associated study:<\/strong> <a>The NAD+\/NADH ratio: linking glycolytic metabolism to transcriptional regulation<\/a><\/p>\n\n\",\"title\":\"\n\n<h3>NAD+ and glycolysis<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>In the mitochondria, NAD+ captures electrons from nutrient oxidation and transfers them to the respiratory chain, thereby supporting ATP production and energy metabolism.<\/p>\n\n\\n\n\n<p><strong>Associated study:<\/strong> <a href=\\\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24125851\/\\\">NAD+ metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus<\/a><\/p>\n\n\",\"title\":\"\n\n<h3>NAD+ and the Krebs cycle (linking reaction)<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>The NADH produced in glycolysis and the Krebs cycle donates its electrons to the electron transport chain, located in the mitochondrial membrane.<br \/>These electrons drive ATP synthase, which produces the majority of ATP required for cellular function.<\/p>\n\n\\n\n\n<p><strong>Associated study:<\/strong> <a href=\\\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29916692\/\\\">Mitochondrial electron transport chain, NAD+ metabolism, and oxidative stress<\/a><\/p>\n\n\",\"title\":\"\n\n<h3>Electron transport chain and oxidative phosphorylation<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>\\nThe NAD+\/NADH pair plays a fundamental role in redox reactions. NAD+ is the oxidized form, and NADH is the reduced form.\\nThese electron exchanges are at the heart of cellular respiration, DNA repair, and the maintenance of redox balance.\\n<\/p>\n\n\\n\n\n<p><strong>Associated study:<\/strong> <a href=\\\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29779976\/\\\" target=\\\"_blank\\\">\\nNAD+ and redox metabolism in aging and disease<\/a><\/p>\n\n\",\"title\":\"\n\n<h3>The redox reaction of NAD+<\/h3>\n\n\"}}]}]}]}],\"name\":\"Les m\u00e9canismes scientifiques du NAD+\"},{\"type\":\"section\",\"props\":{\"id\":\"solutions\",\"image_position\":\"center-center\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"middle\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"Our NAD+ solutions\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"text_align\":\"center\",\"title_color\":\"success\",\"title_element\":\"h2\",\"title_style\":\"h2\"}}]}]},{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"text\",\"props\":{\"block_align\":\"center\",\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>At Yuboost, we go beyond the scientific findings by offering two complementary solutions: <strong>a micronutrient assessment<\/strong> to measure your levels and create a personalized profile, and <strong>intravenous NAD+ infusions<\/strong> to restore your reserves and optimize your performance. By combining analysis with targeted intervention, we help you turn knowledge about NAD+ into real benefits for your health and longevity.<\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"maxwidth\":\"2xlarge\",\"text_align\":\"center\"}}]}]},{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"grid\",\"props\":{\"block_align\":\"center\",\"content_column_breakpoint\":\"m\",\"content_margin_auto\":true,\"css\":\".el-image {\\n    border-radius:20px;}\",\"filter_align\":\"left\",\"filter_all\":true,\"filter_grid_breakpoint\":\"m\",\"filter_grid_width\":\"auto\",\"filter_position\":\"top\",\"filter_style\":\"tab\",\"grid_default\":\"1\",\"grid_medium\":\"2\",\"image_align\":\"top\",\"image_expand\":true,\"image_grid_breakpoint\":\"m\",\"image_grid_width\":\"3-5\",\"image_loading\":true,\"image_svg_color\":\"emphasis\",\"item_animation\":true,\"lightbox_bg_close\":true,\"link_style\":\"default\",\"link_text\":\"Read more\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"maxwidth\":\"2xlarge\",\"meta_align\":\"below-title\",\"meta_element\":\"div\",\"meta_style\":\"text-meta\",\"show_content\":true,\"show_hover_image\":true,\"show_hover_video\":true,\"show_image\":true,\"show_link\":true,\"show_meta\":true,\"show_title\":true,\"show_video\":true,\"title_align\":\"top\",\"title_element\":\"h3\",\"title_grid_breakpoint\":\"m\",\"title_grid_width\":\"1-2\",\"title_hover_style\":\"reset\"},\"children\":[{\"type\":\"grid_item\",\"props\":{\"content\":\"\n\n<p>Accurately measure your NAD+ levels and their cofactors with a quick analysis, then receive a detailed medical interpretation and personalized recommendations to optimize your performance, strengthen your defenses, and preserve cellular longevity.<\/p>\n\n\",\"image\":\"wp-content\/uploads\/2025\/09\/4-1.png\",\"image_alt\":\"bilan nad+\",\"link\":\"https:\/\/yuboost.com\/en\/check-up\/nad\/\",\"link_text\":\"Learn more\",\"title\":\"NAD+ Assessment (At-Home Kit)\"}},{\"type\":\"grid_item\",\"props\":{\"content\":\"\n\n<p>Effectively restore your NAD+ levels by improving mitochondrial health and enhancing cellular repair mechanisms to boost energy production, support mental clarity, and slow the effects of aging.<\/p>\n\n\",\"image\":\"wp-content\/uploads\/2025\/09\/3-1.png\",\"image_alt\":\"perfusion nad\",\"link\":\"https:\/\/yuboost.com\/en\/iv-therapy\/nad\/\/\",\"link_text\":\"Discover the NAD+ infusion\",\"title\":\"Intravenous NAD+ Infusion (Intervention)\"}}]}]}]}],\"name\":\"Nos solutions Yuboost\"},{\"type\":\"section\",\"props\":{\"css\":\".el-section {\\n    padding : 20px;}\",\"image_position\":\"center-center\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"\",\"width\":\"small\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"All about NAD+\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_bottom\":\"medium\",\"margin_top\":\"remove\",\"text_align\":\"left\",\"title_element\":\"h2\",\"title_style\":\"h2\"}}]}]},{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"name\":\"Accordion One Item Start Opened\",\"type\":\"accordion\",\"children\":[{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>It is a coenzyme present in all our cells, essential for energy production and DNA repair.<\/p>\n\n\",\"title\":\"\n\n<h3>What is NAD+ in simple terms?<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>Increased energy, cognitive support, anti-aging effects, physical recovery, and immune protection.<\/p>\n\n\",\"title\":\"\n\n<h3>What are the benefits of NAD+?<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>NAD+ is the oxidized form, NADH is the reduced form, and NADPH is involved in anabolic reactions (synthesis and protection against oxidative stress).<\/p>\n\n\",\"title\":\"\n\n<h3>What is the difference between NAD, NADH, and NADPH?<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>Natural aging, oxidative stress, DNA damage, chronic inflammation, and an unbalanced lifestyle.<\/p>\n\n\",\"title\":\"\n\n<h3>Why do NAD+ levels decrease with age?<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>Low NAD+ levels can be caused by deficiencies in the synthesis\/salvage pathways, excessive DNA damage from free radicals or ultraviolet light, or chronic immune activation.<\/p>\n\n\\n\n\n<p>Activation of PARPs in the presence of excessive or accelerated DNA lesions leads to NAD+ depletion. When NAD+ levels become extremely low, adenosine triphosphate (ATP) production decreases, ATP reserves are consumed, and ultimately, cell death occurs. Increased activity of CD38 and other NAD-consuming ectoenzymes during chronic immune activation also depletes NAD+.<\/p>\n\n\\n\n\n<p>Declining NAD+ levels may be a major factor in aging and age-related degenerative diseases affecting the heart, brain, liver, kidneys, and skin.<\/p>\n\n\",\"title\":\"\n\n<h3>Can NAD+ levels be restored?<\/h3>\n\n\"}},{\"type\":\"accordion_item\",\"props\":{\"content\":\"\n\n<p>Healthy lifestyle (sleep, nutrition, exercise), supplements (NR, NMN), and especially NAD+ IV infusions.<\/p>\n\n\",\"title\":\"\n\n<h3>How to restore NAD+ levels?<\/h3>\n\n\"}}],\"props\":{\"block_align\":\"center\",\"collapsible\":true,\"content_column_breakpoint\":\"m\",\"css\":\".el-title { \\n    font-size : 16px;}\\n.el-content {\\n\\ttext-align: justify;}\",\"id\":\"accordion-behavior-one-item-start-opened\",\"image_align\":\"top\",\"image_grid_breakpoint\":\"m\",\"image_grid_width\":\"1-2\",\"image_svg_color\":\"emphasis\",\"link_style\":\"default\",\"link_text\":\"Read more\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"maxwidth\":\"xlarge\",\"multiple\":true,\"show_image\":true,\"show_link\":false}},{\"type\":\"text\",\"props\":{\"block_align\":\"center\",\"column_breakpoint\":\"m\",\"content\":\"\n\n<p>For more information, contact us at <a href=\\\"mailto:info@yuboost.com\\\">info@yuboost.com<\/a><\/p>\n\n\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"maxwidth\":\"xlarge\"}},{\"type\":\"button\",\"props\":{\"block_align\":\"center\",\"grid_column_gap\":\"small\",\"grid_row_gap\":\"small\",\"margin_bottom\":\"default\",\"margin_top\":\"default\",\"maxwidth\":\"xlarge\",\"text_align\":\"left\",\"text_align_breakpoint\":\"s\",\"text_align_fallback\":\"center\"},\"children\":[{\"type\":\"button_item\",\"props\":{\"button_style\":\"danger\",\"content\":\"Book an appointment\",\"dialog_layout\":\"modal\",\"dialog_offcanvas_flip\":true,\"icon\":\"\",\"icon_align\":\"left\",\"link\":\"https:\/\/yuboost.odoo.com\/\"}}]}]}]}]},{\"type\":\"section\",\"props\":{\"image_position\":\"center-center\",\"style\":\"default\",\"title_breakpoint\":\"xl\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"vertical_align\":\"middle\",\"width\":\"default\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"headline\",\"props\":{\"content\":\"Discover all our vitamins\",\"image_align\":\"left\",\"image_margin\":\"xsmall\",\"margin_bottom\":\"medium\",\"margin_top\":\"remove\",\"text_align\":\"center\",\"title_element\":\"h2\",\"title_style\":\"h2\"}},{\"name\":\"Panel : IV therapies\",\"type\":\"panel-slider\",\"children\":[{\"type\":\"panel-slider_item\",\"props\":{\"content\":\"\",\"image_alt\":\"Hydratation\",\"meta\":\"\"},\"source\":{\"query\":{\"name\":\"posts.customPosts\",\"arguments\":{\"terms\":[10],\"category_operator\":\"IN\",\"post_tag_operator\":\"IN\",\"users\":[],\"users_operator\":\"IN\",\"offset\":0,\"limit\":10,\"order\":\"date\",\"order_direction\":\"DESC\",\"date_range\":\"relative\",\"date_relative\":\"next\",\"date_relative_unit\":\"day\",\"date_relative_unit_this\":\"day\"}}},\"source_extended\":{\"props\":{\"title\":{\"query\":{\"name\":\"#node\"},\"name\":\"title\"},\"image\":{\"query\":{\"name\":\"#node\"},\"name\":\"featuredImage.url\"},\"link\":{\"query\":{\"name\":\"#node\"},\"name\":\"link\"}}}}],\"props\":{\"block_align\":\"center\",\"class\":\"cardyuboost\",\"container_padding_remove\":false,\"content_column_breakpoint\":\"m\",\"content_margin_auto\":true,\"css\":\"\\n\\n.uk-heading-divider {\\n   \\tdisplay: grid;\\n    place-items: center; 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