NAD+: definition, role, benefits, and link to longevity
NAD+ is a vital coenzyme found in all our cells. It supports energy production, DNA repair, mitochondrial function, and contributes to healthy aging.
As we age, its levels decline, which can result in fatigue, cognitive decline, and increased vulnerability to chronic diseases.
Discover our page on NAD+ therapies (IV Therapy), available at home in Switzerland.
Cellular energy production (ATP)
NAD+ acts as a cellular “battery.” It captures and transports electrons during metabolic reactions, enabling the production of ATP, the body’s primary energy source.
During glycolysis and the Krebs cycle, NAD+ is reduced to NADH, which then feeds the mitochondrial respiratory chain and oxidative phosphorylation. This process results in the synthesis of large amounts of ATP.
DNA repair and protection
NAD+ is essential for DNA repair. It serves as a substrate for PARP, an enzyme activated during DNA breaks. At the same time, it activates sirtuins, which regulate gene expression and contribute to longevity mechanisms.
Low levels of NAD+ lead to an accumulation of genetic damage, promoting premature aging, cancer, and degenerative diseases.
Mitochondrial function and oxidative stress
The mitochondria are the “powerhouses” of our cells. NAD+ acts directly by supporting cellular respiration and regulating oxidative stress.
Studies show that increasing NAD+ stimulates mitochondrial biogenesis and activates protective pathways such as PGC1α and sirtuins.
Immune function and neuroprotection
NAD+ also plays a role in immune signaling and the proper functioning of the nervous system. It influences neurotransmitter release and helps protect neurons against oxidative stress.
The benefits of NAD+ in humans
Improves memory, concentration and mental clarity
Contributes to slowing down cellular aging
Promotes physical recovery after sports, stress or burnout
Increases endurance
NAD+ is constantly consumed by all physical and mental functions, and unfortunately, our physiological system uses up NAD+ faster than it can be replenished once we reach our thirties.
The aging process increases the risk of DNA damage, inflammation, and reduced mitochondrial function, which in turn negatively affects the body’s ability to produce NAD+.
On average, NAD+ levels drop by 50% between ages 40 and 60, representing the scientific trigger for the decline of many basic physiological and physical functions.
What is causing the decline of NAD?
Lifestyle choices
Various lifestyle choices can negatively impact our NAD+ levels, such as stress, poor nutrition, an imbalanced work-life schedule, and reduced or poor-quality sleep.
Substance abus
Excessive alcohol, nicotine, recreational drugs, prescription medications, or other substances reduce NAD+ levels.
Aging
Aging is most often associated with a decrease in NAD+ levels. Levels drop by half by middle age, which impacts the body’s ability to combat age-related conditions and diseases.
Chronic diseases
Chronic diseases are generally the result of mitochondrial dysfunction, which can be triggered by a decrease in NAD+ levels.
How to increase your NAD+ levels?
Natural solutions
Natural solutions - Diet rich in vitamin B3 (niacin, tryptophan).
- Regular physical activity.
- Restorative sleep.
- Stress management and a balanced lifestyle.
Supplements and research
Supplements and research NAD+ precursors such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are the subject of numerous studies. They appear promising for supporting NAD+ levels, but research is still ongoing.
NAD+ infusion
NAD+ infusion NAD+ therapy via intravenous infusion is the most effective way to quickly boost NAD+ levels. It delivers NAD+ directly into the bloodstream, providing significant benefits for brain function, energy levels, and overall performance. NAD+ IV Therapy.
NAD+ Assessment (At-Home Kit)
Accurately measure your NAD+ levels and their cofactors with a quick analysis, then receive a detailed medical interpretation and personalized recommendations to optimize your performance, strengthen your defenses, and preserve cellular longevity.
Intravenous NAD+ Infusion (Intervention)
Effectively restore your NAD+ levels by improving mitochondrial health and enhancing cellular repair mechanisms to boost energy production, support mental clarity, and slow the effects of aging.
Discover how YuBoost has improved their daily lives
Je recommande Valiny, qui est une infirmière très douce et de bon conseil.
Je recommande Valiny, qui est une infirmière très douce et de bon conseil.
En résumé, équipe très compétente, très bon suivi après la perfusion 👍
Je recommande !
En résumé, équipe très compétente, très bon suivi après la perfusion 👍
Je recommande !
Cela a amélioré mon efficacité au travail et ma concentration!
Merci à Valiny pour son accompagnement chaleureux et professionnalisme 😄
Cela a amélioré mon efficacité au travail et ma concentration!
Merci à Valiny pour son accompagnement chaleureux et professionnalisme 😄
Yuboost comes straight to your door and offers a variety of IV drips, made me feel like new in no time.
